Thrombolysis

New angiology study results from X. Zhang et al described

Thrombolysis Library Library Home This article was published in Pain & Central Nervous System Week, which you can subscribe to online.

"All the patients were treated with urokinase perfusion through the ophthalmology artery within the first 6 hours after central retinal artery occlusion attack. Conventional treatments including intra-ocular pressure decreasing, microcirculation improvement, neuroprotection and antiplatelet aggregation were conducted. The visual acuity (with International Snellen Chart) and field of vision were detected after thrombolysis. The complications and adverse events were observed. Recanalization was found in 71% of patients. The visual acuity improvement was greater in the recanalization group (n = 35) than in the non-recanalization group (n = 14). The averaged visual acuity was 0.15 +/- 0.02, 0.25 +/- 0.03 and 0.4 +/- 0.05 after 2, 28 days and 6 months, respectively. Of the patients, 24.5% regained > 0.6 of visual acuity, and the visual field deficit was less than 30% in 34.7% of patients after 28 days. Six months later, 36.7% patients regained visual acuity of > 0.6, and the field deficit was less than 30% in 44.9% of patients. The difference between visual acuity in recanalization (0.6 +/- 0.04) and non-recanalization (0.002 +/- 0.0012) patients after 6 months after thrombolysis was significant (p < 0.05). Intra-arterial thrombolysis could obviously improve the short- and long-term visual function for patients with acute central retinal artery occlusion within 6 hours of symptom onset," wrote X. Zhang and colleagues.

The researchers concluded: "[Neurol Res 2009; 31:385-389]'."

Zhang and colleagues published their study in Neurological Research (Intra-arterial thrombolysis for acute central retinal artery occlusion. Neurological Research, 2009;31(4):385-389).

For additional information, contact F. Ling, Capital Med University, Xuanwu Hospital, Dept. of Neurosurgery, Beijing 100053, People's Republic of China.

Publisher contact information for the journal Neurological Research is: Maney Publishing, Ste. 1C, Josephs Well, Hanover Walk, Leeds LS3 1AB, W Yorks, England.

Keywords: People's Republic of China, Beijing, Adverse Drug Effect, Adverse Drug Event, Adverse Drug Reaction, Angiology, Drugs, Hematology, Ischemia, Microcirculation, Neuropathy, Ophthalmology, Optic Nerve Disease, Perfusion, Pharmaceuticals, Retinal Artery, Therapy, Thrombolysis, Thrombolytic, Treatment, Urokinase.

This article was prepared by Pain & Central Nervous System Week editors from staff and other reports. Copyright 2009, Pain & Central Nervous System Week via NewsRx.com.