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Researchers from Sestre Milosrdnice University report recent findings in thrombophilia
2009 JUL 6 - (NewsRx.com) -- According to recent research from Zagreb, Croatia, "The aims of this article are to evaluate the methodological quality of genetic association studies on the inherited thrombophilia published during 2003 to 2005, to identify the most common mistakes made by authors Of those Studies, and to examine if overall quality of the article correlates with the quality of the journal. Articles were evaluated by 2 independent reviewers using the checklist of 16 items." "A total of 58 eligible studies were identified. Average total score was 7.59 +/- 1.96. Total article score did not correlate with the journal impact factor (r = 0.3971; 95% confidence interval [C1], 0.1547-0.5944, P =.002). Total score did not differ across years (P =.624). Finally, it is concluded that methodological quality of genetic association Studies is not optimal, and it does not depend on the quality of the journal," wrote A.M. Simundic and colleagues, Sestre Milosrdnice University. The researchers concluded: "Journals should adopt methodological criteria for reporting the genetic association Studies, and editors should encourage authors to strictly adhere to those criteria." Simundic and colleagues published their study in Clinical and Applied Thrombosis - Hemostasis (Methodological Issues in Genetic Association Studies of Inherited Thrombophilia: Original Report of Recent Practice. Clinical and Applied Thrombosis - Hemostasis, 2009;15(3):327-333). For additional information, contact A.M. Simundic, Sestre Milosrdnice University Hospital, Institute Clinic Chemical, Vinogradska 29, Zagreb 10000, Croatia. Publisher contact information for the journal Clinical and Applied Thrombosis - Hemostasis is: Sage Publications Inc., 2455 Teller Rd., Thousand Oaks, CA 91320, USA. Keywords: Croatia, Zagreb, Clinical Trial Research, Thrombophilia, Thrombosis, Sestre Milosrdnice University. This article was prepared by Biotech Business Week editors from staff and other reports. Copyright 2009, Biotech Business Week via NewsRx.com.
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