Researchers from Princess Margaret Hospital publish new studies and findings in the area of thrombocytopenic purpura
2007 OCT 29 -- According to a study from Hong Kong, People's Republic of China, "'Thrombotic thrombocytopenic purpura (TTP) is a rare but potentially fatal disease in childhood. The association of microangiopathic hemolytic anemia, schistocytes, and thrombocytopenia without fever, neurologic, and renal involvement is sufficient to suspect TTP at an early stage for prompt plasma infusion or exchange therapy." "TTP has been increasingly described especially in association with systemic lupus erythematosus (SLE). We report the youngest Chinese boy who presented his SLE with TTP and subsequently experienced 9 relapses of TTP in a 2-year period. SLE disease activity index was low during his TTP relapses and therefore alertness of TTP relapse is required even in a relatively inactive period of SLE," wrote L.K. Yuen and colleagues, Princess Margaret Hospital. The researchers concluded: "TTP should be recognized even without renal or neurologic features and can respond to plasma therapy." Yuen and colleagues published the results of their research in Jcr - Journal of Clinical Rheumatology (Thrombotic thrombocytopenic purpura in a young boy with systemic lupus erythematosus. Jcr - Journal of Clinical Rheumatology, 2007;13(4):224-228). For additional information, contact L.K. Yuen, Princess Margaret Hospital, Dept. of Pediatrics & Adolescent Medical, Lai King Hill Rd., Kowloon, Hong Kong, People's Republic of China. The publisher of the Jcr - Journal of Clinical Rheumatology can be contacted at: Lippincott Williams & Wilkins, 530 Walnut St., Philadelphia, PA 19106-3621, USA. Keywords: People's Republic of China, Hong Kong, Hematology, Rheumatology, Systemic Lupus Erythematosus, Thrombocytopenic Purpura, Princess Margaret Hospital. This article was prepared by Hematology Week editors from staff and other reports. Copyright 2007, Hematology Week via NewsRx.com.
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