Thrombotic Thrombocytopenic Purpura


New thrombocytopenic purpura cell biology research from Gaziantep University, Department of Medical Oncology discussed



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This article was published in Clinical Oncology Week, which you can subscribe to online.

2007 OCT 15 -- Data detailed in 'Thrombotic thrombocytopenic purpura and bone marrow necrosis as the initial presentation of lung cancer' have been presented. According to a study from Gaziantep, Turkey, "Thrombotic thrombocytopenic purpura (TTP) is a disseminated form of thrombotic microangiopathy. Although most cases are held to be idiopathic, its association with malignancy is well recognized, and it usually occurs at the terminal stage of cancer."

"Bone marrow necrosis (BMN) is another rare disorder defined pathologically as the necrosis of myeloid tissue and medullary stroma with preservation of bone. Although hematologic malignancy is the most common underlying disease associated with BMN, it can also be caused by solid tumors. The occurrence of TTP with BMN associated with lung cancer has not been reported in the English literature," wrote A. Sevinc and colleagues, Gaziantep University, Department of Medical Oncology.

The researchers concluded: "First described is a patient with the rare association of TTP and BMN displayed as the first manifestations of a lung cancer."

Sevinc and colleagues published their study in Clinical and Applied Thrombosis (Thrombotic thrombocytopenic purpura and bone marrow necrosis as the initial presentation of lung cancer. Clinical and Applied Thrombosis, 2007;13(4):449-52).

For more information, contact A. Sevinc, Gaziantep Oncology Hospital, Dept. of Medical Oncology, Gaziantep University, School of Medicine, Gaziantep, TR-27310, Turkey.

Publisher contact information for the journal Clinical and Applied Thrombosis is: Westminster Publ Inc., 708 Glen Cove Avenue, Glen Head, NY 11545, USA.

Keywords: Turkey, Gaziantep, Thrombocytopenic Purpura Cell Biology, Bone Marrow, Cell Biology, Hematology, Lung Cancer, Lung Neoplasms, Necrosis, Oncology, Thrombocytopenic Purpura, Thrombosis.

This article was prepared by Clinical Oncology Week editors from staff and other reports. Copyright 2007, Clinical Oncology Week via NewsRx.com.