Studies in the area of thrombocytopenic purpura immunology reported from St. Louis University, Department of Internal Medicine
2007 SEP 24 -- Research findings, "Thrombotic thrombocytopenic purpura and graves disease," are discussed in a new report. "Patients with an autoimmune disease have a propensity for development of a second autoimmune disease. We report the first instance of a patient with both idiopathic thrombotic thrombocytopenic purpura (TTP) and Graves disease," scientists in the United States report. "The TTP remitted with a combination of plasmapheresis and prednisone. Methimazole led to sustained remission of the hyperthyroid state within 6 weeks," wrote B.T. Chaar and colleagues, St. Louis University, Department of Internal Medicine. The researchers concluded: "Although hyperthyroidism may induce immune imbalance causing autoimmunity, it is unclear if this influenced the development of TTP in our patient and if treatment of hyperthyroidism alone could have resulted in the cure of both diseases." Chaar and colleagues published their study in The American Journal of the Medical Sciences (Thrombotic thrombocytopenic purpura and graves disease. The American Journal of the Medical Sciences, 2007;334(2):133-5). For additional information, contact B.T. Chaar, Saint Louis University School of Medicine, Dept. of Internal Medicine, Saint Louis, Missouri 63110 USA.. The publisher's contact information for the The American Journal of the Medical Sciences is: Lippincott Williams & Wilkins, 530 Walnut St., Philadelphia, PA 19106-3621, USA. Keywords: United States, Saint Louis, Thrombocytopenic Purpura Immunology, Autoimmune Disease, Autoimmune Disorder, Endocrinology, Graves Disease, Graves' Disease, Hematology, Immunology, Thrombocytopenic Purpura. This article was prepared by Hematology Week editors from staff and other reports. Copyright 2007, Hematology Week via NewsRx.com.
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