Thymoma
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New neuropathy data have been reported by scientists at Humanitas Clinical Institute
2009 JUL 20 - (NewsRx.com) -- According to a study from Milan, Italy, "Along with myasthenia, other paraneoplastic neurological syndromes (PNS) may occur in thymoma. Anti-Hu antibodies and a clinical ''anti-Hu syndrome'' characterized by encephalitis and/or painful neuropathies have been reported in only three patients at the time of the diagnosis of thymoma." "We describe a severe anti-Hu-related autonomic neuropathy with gastrointestinal paresis and intestinal pseudo-obstruction with malabsorption that occurred concomitantly with the worsening of myasthenic symptoms long after the initial diagnosis of thymoma in a Young patient. The clinical anti-Hu syndrome preceded the radiological diagnosis of thymoma recurrence," wrote M. Simonelli and colleagues, Humanitas Clinical Institute. The researchers concluded: "Treatment with plasma exchange led to a transient improvement of neurological symptoms." Simonelli and colleagues published the results of their research in Tumori (Thymoma associated with myasthenia and autonomic anti-Hu paraneoplastic neuropathy. Tumori, 2009;95(2):243-247). For additional information, contact M. Simonelli, Humanitas Clinical Institute, Dept. of Med Oncology & Hematology, Via Manzoni 56, I-20089 Milan, Italy. The publisher of the journal Tumori can be contacted at: Pensiero Scientifico Editor, Via Bradano 3, C, 00199 Rome, Italy. Keywords: Italy, Milan, Anti-Hu Syndrome, Central Nervous System Disease, Encephalitis, Gastroenterology, Myasthenia, Neurology, Neuropathy, Thymoma, Humanitas Clinical Institute. This article was prepared by Pain & Central Nervous System Week editors from staff and other reports. Copyright 2009, Pain & Central Nervous System Week via NewsRx.com.
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