New hyperparathyroidism study results from Johns Hopkins University, Medical Department described
2009 AUG 3 - (NewsRx.com) -- In this recent article published in the journal Endocrine Practice, scientists in the United States conducted a study "To report an unusual Occurrence of recurrent hyperparathyroidism due to papillary thyroid carcinoma. We describe the clinical history, physical examination findings, laboratory values, imaging findings, and pathologic findings of it woman who developed recurrent hyperparathyroidism 13 years after successful parathyroidectomy." "A 59-year-old woman presented to Our clinic with recurrent primary hyperparathyroidism. In 1994, she presented with nephrolithiasis and underwent resection of a right superior parathyroid adenoma that resulted in clinical and biochemical cure. Her clinical course had been followed at periodic intervals,and she had been symptom-free and normocalcemic. In 2007, she again developed nephrolithiasis and was documented to have recurrent hyperparathyroidism. Imaging studies suggested a parathyroid adenoma near the right inferior pole of the thyroid. The patient had reoperative neck exploration. No obvious parathyroid adenoma was found and a right thyroid lobectomy was performed, which resulted in normalization of intraoperative intact parathyroid hormone levels, and the incision was closed. Final pathology demonstrated no parathyroid adenoma, but instead, a 1-cm papillary thyroid carcinoma that stained positive for parathyroid hormone. More than 6 months after Surgery, she remains clinically and biochemically cured. Recurrent hyperparathyroidism occurs secondary to multiple causes," wrote S.Y. Morita and colleagues, Johns Hopkins University, Medical Department. The researchers concluded: "This case demonstrates the challenge a surgeon faces in managing recurrent disease and highlights a rare phenomenon of papillary thyroid cancer causing recurrent hyperparathyroidism. (Endocr Pract. 2009; 15:349-352)." Morita and colleagues published their study in Endocrine Practice (AN UNUSUAL CASE OF RECURRENT HYPERPARATHYROIDISM AND PAPILLARY THYROID CANCER. Endocrine Practice, 2009;15(4):349-352). Additional information can be obtained by contacting M.A. Zeiger, Johns Hopkins University, Endocrine Surgery Sect, School Medical, Dept. of Surgery, 600 N Wolfe St., Baltimore, MD 21287, USA. The publisher of the journal Endocrine Practice can be contacted at: American Association Clinic Endocrinol, 1000 Riverside Avenue, Ste. 205, Jacksonville, FL 32204, USA. Keywords: United States, Baltimore, Adenoma, Biochemical, Endocrine, Endocrinology, Hyperparathyroidism, Kidney Calculi, Nephrolithiasis, Oncology, Papillary Thyroid Cancer, Parathyroidectomy, Primary Hyperparathyroidism, Surgery, Thyroid Carcinoma, Thyroid Neoplasms, Johns Hopkins University, Medical Department. This article was prepared by Clinical Oncology Week editors from staff and other reports. Copyright 2009, Clinical Oncology Week via NewsRx.com.
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