Scientists at Catholic University discuss research in biopsy
2009 JUL 28 - (NewsRx.com) -- According to a study from Rome, Italy, "Ultrasonography-guided fine needle aspiration (FNA) and fine needle non-aspiration (FNNA) biopsy were performed consecutively on 104 patients (mean age 50 +/- 15 years) affected by multinodular and uninodular goiter. Both techniques were executed on the same patients in the same clinical session beginning with the first (FNA) on half of the patients (randomly selected) and vice versa." "The cytological findings on cell samples were divided into four groups: colloidal (benign), follicular (suspicious), malignant, and inadequate. The overall cytologic findings obtained with the two techniques were as follows (FNA % vs FNNA %): inadequate, 16.3% vs 5.8%; colloidal, 69.2% vs 76.9%; follicular, 9.6% vs 10.5%; and malignant, 4.8% vs 6.7%. A statistically significant difference between FNA and FNNA cytology was found only on the number of inadequate results (p = 0.015). Interestingly, the frequency of inadequate specimens for FNNA showed a significantly different distribution depending on the sequence (first or second) in which the technique was executed," wrote F. Romitelli and colleagues, Catholic University. The researchers concluded: "FNA and FNNA are useful and cost-effective techniques for the pre-operative assessment of patients with thyroid nodules. However, due probably to its minimally invasive procedure, FNNA produces specimens of better quality and reduces inadequate results. For these reasons FNNA should be preferable to FNA for the cytological evaluation of thyroid nodules." Romitelli and colleagues published their study in Endocrine Pathology (A Comparative Study of Fine Needle Aspiration and Fine Needle Non-Aspiration Biopsy on Suspected Thyroid Nodules. Endocrine Pathology, 2009;20(2):108-113). For more information, contact F. Romitelli, Sacred Heart Catholic University, Institute Biochemistry & Clinic Biochemistry, Largo Vito 1, I-00168 Rome, Italy. Publisher contact information for the journal Endocrine Pathology is: Humana Press Inc., 999 Riverview Drive Suite 208, Totowa, NJ 07512, USA. Keywords: Italy, Rome, Biopsy, Colloid, Cytology, Diagnostics, Endocrine, Medical Device, Nodular Goiter, Pathology, Surgery, Thyroid Nodule, Catholic University. This article was prepared by Life Science Weekly editors from staff and other reports. Copyright 2009, Life Science Weekly via NewsRx.com.
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