New research on metabolism from A. Wisniewski and co-authors summarized
2007 AUG 7 -- New research, "Weight deficit at birth and Turner's syndrome," is the subject of a report. "Turner's syndrome (TS) is one of the most frequent diseases accompanied by growth deficiency. Though developmental disorders have been observed in the fetal period, there has been disagreement as to whether short stature is frequent in newborn girls with Turner's syndrome," scientists writing in the Journal of Pediatric Endocrinology & Metabolism report. "Hence we attempted to determine the incidence of 'small for gestational age' in TS compared with healthy newborns girls delivered at term above -2 SD (body length and weight) for gestational age. The medical records of 548 girls with TS recruited from Polish university and district hospitals were screened, with 468 of them delivered at term (gestational age >or=38 weeks) being included in this study. Mean weight (±SD) at birth was 2963 ±444 g, which was below the normal value for gestational age in nearly 90%. The mean birth weight deficiency was 600 g, but exceeded 1000 g in over 10%. When a newborn girl delivered at term has a marked weight deficit, Turner's syndrome should be considered. This is especially so when the girl is a product of a first pregnancy, when routine karyotyping is recommended," wrote A. Wisniewski and colleagues, . The researchers concluded: "The condition may arise from a partial dysfunction of a gene or genes on the X-chromosome involved in the control of fetal growth." Wisniewski and colleagues published their study in the Journal of Pediatric Endocrinology & Metabolism (Weight deficit at birth and Turner's syndrome. Journal of Pediatric Endocrinology & Metabolism, 2007;20(5):607-13). Additional information can be obtained by contacting A. Wisniewski, Academy of Physical Education 34 Marymoncka, Dept. of Physiology, 00-968 Warsaw, Poland. The publisher of the Journal of Pediatric Endocrinology & Metabolism can be contacted at: Freund Publishing House Ltd., Ste. 500, Chesham House, 150 Regent St., London W1R 5FA, England. Keywords: Poland, Warsaw, Endocrinology, Genetics, Metabolism, Pediatric, Turner Syndrome, Wellness. This article was prepared by Life Science Weekly editors from staff and other reports. Copyright 2007, Life Science Weekly via NewsRx.com.
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