Research from Federal University of Minas Gerais yields new data on contagious ecthyma
2009 AUG 4 - (NewsRx.com) -- "Orf virus (ORFV), the prototype of the genus Parapoxvirus (PPV), is the etiological agent of contagious ecthyma, a severe exanthematic dermatitis that afflicts domestic and wild small ruminants. Although South American ORFV outbreaks have occurred and diagnosed there are no South American PPV major membrane glycoprotein B2L gene nucleotide sequences available," scientists in Belo Horizonte, Brazil report. "presentation: an outbreak of ovine contagious ecthyma in Midwest Brazil was investigated. The diagnosis was based on clinical examinations and molecular biology techniques. The molecular characterization of the virus was done using PCR amplification, cloning and DNA sequencing of the B2L gene. The phylogenetic analysis demonstrated a high degree of identity with ORFV strains, and the isolate was closest to the ORFV-India 82/04 isolate. Another Brazilian ORFV isolate, NE1, was sequenced for comparative analysis and also showed a high degree of identity with an Asian ORFV strain. Distinct ORFV strains are circulating in Brazil," wrote J.S. Abrahao and colleagues, Federal University of Minas Gerais. The researchers concluded: "This is the first report on the phylogenetic analysis of an ORFV in South America.." Abrahao and colleagues published their study in Virology Journal (Detection and phylogenetic analysis of Orf virus from sheep in Brazil: a case report. Virology Journal, 2009;6():47). For more information, contact E.G. Kroon, Federal University of Minas Gerais, Institute Ciencias Biology, Dept. of Microbiology, Virus Laboratory, Av Antonio Carlos 6627, Caixa Postal 486, BR-31270901 Belo Horizonte, MG, Brazil. Publisher contact information for the Virology Journal is: Biomedical Central Ltd., Current Science Group, Middlesex House, 34-42 Cleveland St., London W1T 4LB, England. Keywords: Brazil, Belo Horizonte, Contagious Ecthyma, Dermatitis, Dermatology, Virology, Federal University of Minas Gerais. This article was prepared by Life Science Weekly editors from staff and other reports. Copyright 2009, Life Science Weekly via NewsRx.com.
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