Cancer Vaccine

Phase I study for antitumor CEA-TRICOM published

Published in AIDS Vaccine Week, January 17th, 2005

Researchers led by John L. Marshall, MD of Georgetown University published the results of a phase I study demonstrating the safety and antitumor activity of Therion Biologics' CEA-TRICOM therapeutic cancer vaccine in the Journal of Clinical Oncology.

The phase I study evaluated multiple dosing regimens of the CEA-TRICOM vaccines in 58 patients with advanced CEA-expressing tumors. Investigators found that disease stabilization was achieved for at least 4 months in 40% of the study participants, and for more than 6 months in 24% of the participants.

One patient with small cell lung cancer achieved a complete response, with no evidence of cancer...

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Source: AIDS Vaccine Week (2005-01-17)

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