Published in AIDS Vaccine Week, October 31st, 2005
Study 1: Systemic mobilization of antigen-presenting cells, with a chimeric FLT-3 and G-CSF receptor agonist, during immunization of Macaca mulatta with HIV-1 antigens, is insufficient to modulate immune responses or vaccine efficacy.
According to a study from the Netherlands, United States, and Germany, "In order to improve the efficacy of current vaccine candidates against HIV/AIDS, we sought to strengthen the induction of immune responses via simultaneous in vivo mobilization of dendritic cells using a chimeric Flt-3 and G-CSF receptor...
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