Published in AIDS Vaccine Week, September 4th, 2006
Study 1: Stavudine-loaded mannosylated liposomes have anti-HIV-I activity and improved systemic clearance.
According to a study from India, "Cells of the mononuclear phagocyte system (MPS) are important hosts for human immunodeficiency virus (HIV). Lectin receptors, which act as molecular targets for sugar molecules, are found on the surface of these cells of the MPS."
"Stavudine-loaded mannosylated liposomal formulations were developed for targeting to HIV-infected cells. The mannose-binding protein concanavalin A was employed as model system for the...
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Source: AIDS Vaccine Week (2006-09-04)
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