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HIV/AIDS Therapy

Studies from Institute Pasteur further understanding of HIV/AIDS therapy

Published in AIDS Vaccine Week, August 27th, 2007

Data detailed in "Presence of HIV-1 Nef specific CD4 T cell response is associated with non-progression in HIV-1 infection" have been presented. "The ex vivo response to three HLA-DR-restricted Nef peptides (Nef 66-97, Nef 133-159, Nef 180-202) and one HLA-DQ-restricted Nef peptide (Nef 56-68) was evaluated in 28 HIV-seropositive patients and 6 Long-term Non-Progressors (LTNPs). Analyzing specific proliferative response and IFN-gamma secretion, patients were identified as high responders, medium responders and non-responders to peptides," scientists in Lille, France report.

"As high responder patients, LTNP patients showed strong proliferative response to all the...

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