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HIV/AIDS Vaccines

Reports outline HIV/AIDS vaccines study findings from G. Devitt and colleagues

Published in AIDS Vaccine Week, August 27th, 2007

Fresh data on HIV/AIDS are presented in the report "Analysis of the exposure of induced HIV glycoprotein epitopes in a potential HIV pseudovirion vaccine." According to recent research from Heidelberg, Germany, "Functionally conserved HIV-Env epitopes, which are induced during the process of Env-mediated membrane fusion, represent interesting immunogens, which may elicit broad neutralising antibody responses. In this report, we analyse a pseudovirion (PV)-based HIV vaccine preparation, potentially enriched in such induced Env-conformations."

"The vaccine has been prepared by mixing and incubating Env-PVs, with incorporated fusion-defective Env, with PVs, which have...

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