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Endocrinology

"Low adrenal Androgens in Men with HIV Infection and the Acquired Immunodeficiency Syndrome."

Published in AIDS Weekly Plus, August 7th, 1995

According to the authors' abstract of an article published in Hormone Research, "Using gas chromatography and mass spectrometry we have studied the ratios of steroid metabolites and 24-hour urinary steroid excretion rates in 37 men of whom 14 where positive for the human immunodeficiency virus (HIV; group A), while 9 had acquired immunodeficiency syndrome (AIDS; group B). Controls were sick non-AIDS patients admitted to an intensive care unit (ICU) and healthy volunteers. In groups A and B and the ICU controls, there was a reduction in the excretion of adrenal androgen metabolites and a reduced ratio of 5 alpha to 5 beta androgen metabolites. These data suggest that adrenal androgens...

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