National University of Ireland Maynooth
Antisera-based immunoassay effective for aspergillosis diagnosis
Published in AIDS Weekly and Law, April 22nd, 2004
According to recent research from Ireland, "[i]mmunological detection of secreted low molecular weight toxins represents a potentially novel means of diagnosing infection by the fungus Aspergillus fumigatus."
"Two such metabolites, gliotoxin and helvolic acid, were selected and conjugated to thyroglobulin for antisera generation in rabbits," in a study conducted by M. Fox and coauthors at the National University of Ireland Maynooth.
"Gliotoxin was initially activated using N-[p-maleimidophenyl] isocyanate (PMPT) and subsequently conjugated to...
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Source: AIDS Weekly and Law (2004-04-22)
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