Academic Medical Centre, Amsterdam
Subtype-specific transcriptional promoters determine replication rate
Published in AIDS Weekly and Law, May 13th, 2004
In a study from the Netherlands, the LTR "transcriptional promoters of different human immunodeficiency virus (HIV) type 1 subtypes were inserted into the LAI molecular clone of subtype B.
"The viral genotypes represent seven subtypes (A, B, C, D, E, F, and G) and one circulating recombinant form (AG)," explained T. van Opijnen and coauthors working at the University of Amsterdam's Academic Medical Centre. The collaborators "performed replication studies with this isogenic set of viruses across six cellular...
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Source: AIDS Weekly and Law (2004-05-13)
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