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AIDS Weekly and Law

Susan Hasty, Publisher

Table of Contents . . . September 2nd, 2004

Non-Subscriber - Summaries Only

Related Areas: Other Issues in AIDS Weekly and Law | Other Publications

Abbott Laboratories - Government decides not to intervene and force down AIDS drug price

Crucell Holland BV - Challenges in the search for HIV vaccine outlined

Harris Interactive - Americans support HIV/AIDS prevention programs

Ranbaxy - Audit of HIV/AIDS drug manufacturing reveals anomalies

U.S. Centers for Disease Control & Prevention - American Indians and Alaska natives surveilled for HIV/AIDS and risk behaviors

Advanced Viral Research Corp. - Patient enrollment completed clinical trial of AVR118 in patients with AIDS

Centre Hospitalier National Souro Sanou, Burkina F - Guillain-Barre syndrome strongly associated with HIV infection in young adults

CHUL Research Center, St. Foy - Envelope glycoproteins not required for insertion of host ICAM-1 into HIV-1

Chulalongkorn University, Bangkok - HIV prevention plus need for medical management remains a challenge in Asia

Dana Farber Cancer Institute - N-linked glycosylation in CXCR4 N-terminus inhibits HIV-1 env gp binding

Dermik Laboratories - FDA approves Sculptra (injectable poly-L-lactic acid)

Drexel University - HIV-specific CD8+ T cells exhibit markedly reduced levels of Bcl-2 and Bcl-xL

Emory University - Mast cells may serve as a viral reservoir for HIV-1

Fred Hutchinson Cancer Research Center - Early HIV-1 diversity not restricted to certain risk groups/subtypes

Gilead Sciences, Inc. - FDA approves two fixed-dose combination drug products for HIV-1 infection

Gilead Sciences, Inc. - U.S. FDA approves Truvada as part of HIV combination therapy

Harvard University - Predicted efficacy of HAART for HIV-1 infection not as efficacious against HIV-2

Healthcare Coverage - Rwanda to offer free generic drugs to HIV/AIDS patients

HIV/AIDS - 56% of surveyed African Americans say U.S. is losing ground on HIV/AIDS

HIV/AIDS - Women are forgotten HIV/AIDS patients in Zambia

HIV/AIDS Prevention - New Zealand prime minister urges Pacific nations to take action against AIDS

HIV/AIDS Treatment - Cuts to health programs could create backlog of HIV patients

Infertility - National guidelines expected to promote ART best practices

Institute Tropical Medicine, Antwerp - Comprehensive strategy needed to access antiretroviral treatment in South Africa

Institute Veille Sanitaire, Maurice - Education campaigns necessary as HIV transmission increases in Western Europe

Johns Hopkins University - Multiple HIV-1 Nef functions contribute to efficient replication in macrophages

Knox College - U937 cytokine secretion inhibited by HIV-1 gp120 C4-derived peptide constructs

Korea Advanced Institute Science and Technology, T - KSHV evolved a unique tactic for its stable maintenance

Kyushu University - Soybean protein diet protects against methotrexate toxicity

Mayo Clinic - Fungal pheromone receptor PCSTE3 from P. carinii cloned and characterized

Medical University of Gdansk - Novel benzodithiazines are nontoxic and have anti-HIV-1 integrase activity

MedMira Inc. - Sales of MedMira Rapid HIV Tests start in Canada

Peking University, Beijing - Morphine prolongs survival of SIV-infected cells in early infection

Queen Sirikit National Institute of Child Health - Condom use reduces rate of new HIV infections in Thailand

Seoul National University - EE155 region has important role in down-regulation of CD4 by HIV-1 Nef protein

Starpharma Holdings Limited - HIV prevention drug gets U.S. FDA clearance to advance in phase 1 clinical trial

State University of New York, Buffalo - Malnutrition increases risk of acquired immunodeficiency syndrome

U.S. National Institutes of Health - Noninfectious X4 but not R5 HIV-1 inhibits lymphoid tissue antibody response

U.S. World Health Organization - US$5-6 billion needed by 2005 to provide ART to low-, middle-income countries

Univ. London School Hygiene/Tropical Med. - Potentially preventable infections are leading cause of HIV-related deaths

University Franche Comte, Besancon - CD4+ and CD8+ T cell apoptosis inhibited by CXCR4 blockade in HIV-infected cells

University of Alabama - YMDD aspartates of p66 are required and sufficient for RT polymerase function

University of Amsterdam - HIV-1 promoter contains a CATA box for optimal transcription and replication

University of Barcelona - Pancreatitis associated with didanosine plus tenofovirin in HIV infection

University of Birmingham - CD8+ T-cell immunity to cytomegalovirus reviewed

University of California San Diego - Mobilization of antiretroviral SIV gene therapy vector is feasible

University of California, Davis - Abundant expression of granzyme A but not perforin in CD8+ cell granules in GALT

University of California, Los Angeles - alpha- and theta-defensins bind with high affinity to HIV-1 gp120

University of California, San Francisco - Maximal rate of HIV protease inhibitor resistance occurs at 87% adherence

University of Colorado - Antigen reexposure has role in immune reconstitution in pediatric HIV infection

University of Colorado - HAART does not prevent herpes zoster infection in HIV-infected children

University of Edinburgh - LANA isoform may perform alternative functions in KSHV-infected cells

University of Lausanne - Cytomegalovirus-specific cellular immune responses reviewed

University of Laval, Quebec City - Endosome disruption enhances functional nuclear delivery of Tat-fusion proteins

University of Los Andes, Merida - Fas-mediated apoptosis increased in PMNs from HIV-infected patients

University of Minnesota -  Entamoeba lectin epitopes recognized by human IgA antibodies identified

University of Ottawa - IFN-gamma-induced inhibition of HIV replication mediated before virus entry

University of Pennsylania - Brownian adhesive dynamics (BRAD) simulate receptor-mediated binding of viruses

University of Pennsylvania - Adoptive transfer of activated autologous CD4+ cells can augment immune system

University of Puerto Rico, San Juan - HIV status disclosure improves therapy adherence in adolescents

University of Texas Medical Branch - Reduced glutathione and cysteine levels associated with HIV disease progression

University of Tokyo - T cell-based control of SIV replication in AIDS vaccine trial reported

University of Ulm Klinikum - Functional SIV nef genes allow for efficient zoonotic infection in humans

University of Virginia - Glutamine or alanyl-glutamine improves GI symptoms and increases ART levels

University of Washington - HIV RNA higher in rectal mucosa than blood/seminal plasma independent of ART

University of Washington - HSV-2 infection increases risk of HIV transmission

University of Washington - Purifying selection masks mutational flexibility of HIV-1 reverse transcriptase

Virgen del Rocio University Hospital, Seville -  P. jiroveci polymorphisms suggest common infection source among disease type

VIRxSYS Corp. - HIV-1-based vector used to develop mutants incapable of developing resistance

VIRxSYS Corp. - Lentivirus-based antisense vector inhibits HIV replication

Washington University - HIV Env-coreceptor interactions help mediate virus-cell/cell-cell fusion

Weatherall Institute of Molecular Medicine, Oxford - DNA prime-MVA boost HIV vaccine tailored for eastern and central Africa

Yale University - Sustained benefit of HAART lost when prisoners return to community

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