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Vertex Pharmaceuticals Incorporated

Data supports development of investigational HIV protease inhibitor brecanavir

Published in AIDS Weekly and Law, January 19th, 2006

GlaxoSmithKline (GSK) and Vertex Pharmaceuticals Incorporated (VRTX) have presented positive results from a study evaluating the safety, tolerability, and antiviral activity of the investigational HIV-1 protease inhibitor (PI), brecanavir (formerly known as GW640385 or VX-385).

These data were presented at the 45th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) held in Washington DC. Interim findings following 24 weeks of dosing demonstrated potent antiviral activity for brecanavir in both PI-sensitive and PI-resistant HIV-infected adults.

"These results support the ongoing development program for brecanavir, which is...

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