Published in AIDS Weekly and Law, March 30th, 2006
The viral RNase_H has been shown to be essential for HIV replication. There are no inhibitors of HIV-1 RNase_H in clinical development at this time. In fact, very few such inhibitors have even been identified for this target. Successful development of this drug will play an important role in the treatment of AIDS patients who have become resistant to current therapy. Projected revenue for an orally bioavailable (first in class) drug for AIDS is estimated at $350-$500 million U.S.
The current market of AIDS drugs is $6...
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