AIDS Research Center, Palo Alto
Hepatitis C virus protease gene diversity exists in HIV coinfection
Published in AIDS Weekly and Law, June 8th, 2006
"The clonal variability of the HCV protease gene in 24 individuals with HCV genotypes 1a, 1b, 2b, and 3a who were coinfected with the human immunodeficiency virus was evaluated," wrote M.A. Winters and colleagues, AIDS Research Center.
"Within-genotype variability at the nucleotide and amino acid levels ranged from 6.5 to 8.6% and 2.2 to 3.8%, respectively. After adjustments were made for correlation of intrapatient clonal variation, mixed-model analysis indicated that nucleotide and...
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Source: AIDS Weekly and Law (2006-06-08)
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