Published in AIDS Weekly and Law, September 7th, 2006
Study 1: Toll-like receptor agonists influence the magnitude and quality of memory T cell responses after prime-boost immunization in nonhuman primates.
"There is a remarkable heterogeneity in the functional profile (quality) of T cell responses. Importantly, the magnitude and/or quality of a response required for protection may be different depending on the infection. We assessed the capacity of different Toll like receptor (TLR)-binding compounds to influence T helper cell (Th) 1 and CD8+ T cell responses when used as adjuvants in nonhuman primates (NHP) with HIV Gag as a...
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Source: AIDS Weekly and Law (2006-09-07)
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