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HIV/AIDS

Pfizer's Maraviroc to Receive Accelerated Regulatory Reviews in the U.S. and Europe

Published in AIDS Weekly and Law, March 8th, 2007

Pfizer announced that marketing authorization applications for maraviroc will receive accelerated review in both the United States and Europe. Accelerated reviews are granted to potential medicines that, if approved, would represent significant improvements over current therapies.

If approved by the regulatory agencies, maraviroc will be the first in a new class of HIV/AIDS treatments called CCR5 antagonists that work by blocking viral entry. Rather than fighting HIV inside white blood cells, CCR5 antagonists prevent the virus produced by infected cells from entering uninfected cells by blocking its predominant entry route, the CCR5 co- receptor.

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