HIV/AIDS
Reports summarize HIV/AIDS research from University of Michigan
Published in AIDS Weekly and Law, July 5th, 2007
Fresh data on HIV/AIDS are presented in the report "Probing Na(+)-induced changes in the HIV-1 TAR conformational dynamics using NMR residual dipolar couplings: new insights into the role of counterions and electrostatic interactions in adaptive recognition." According to recent research published in the journal Biochemistry, "Many regulatory RNAs undergo large changes in structure upon recognition of proteins and ligands, but the mechanism by which this occurs remains poorly understood. Using NMR residual dipolar coupling (RDCs), we characterized Na+-induced changes in the structure and dynamics of the bulge-containing HIV-1 transactivation response element (TAR) RNA that mirrors...
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Source: AIDS Weekly and Law (2007-07-05)
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