Adverse Drug Reactions

Investigators at Royal Children's Hospital target adverse drug reactions in children

Published in AIDS Weekly and Law, November 12th, 2009

A new study, 'Toxicity of first-line drugs for treatment of tuberculosis in children: review,' is now available. "To determine the frequency and manifestations of adverse events associated with recommended first-line anti-TB drugs in children. Literature review. Overall, children tolerate anti-TB drugs very well when using currently recommended dosages," scientists in Melbourne, Australia report.

"Serious adverse events are rare and even mild symptoms such as nausea or vomiting are uncommon. There are occasional case reports of severe hepatotoxicity. Surveillance and reporting of adverse events will need to be improved when recommended dosages of the main first-line...

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Source: AIDS Weekly and Law (2009-11-12)

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