"Macaque Rectal Mucosa: A Model System for HIV Rectal Transmission."

According to a abstract presented by the authors to the Mucosal Immunity: New Strategies for Protection against Viral and Bacterial Pathogens Keystone Symposia, held January 16-23, 1995, in Keystone, Colorado, "The most common route of transmission of HIV is the mucosal route. There are theoretically four ways for a lymphotropic virus to cross the epithelial barrier: lesion in the epithelium, infection of the epithelial cells, transcytosis of virions in epithelial cells and uptake of virions by cells of the mucosal immune surveillance (M cells or Langerhans cells). Each route of entry will lead initially to the infection of a different subset of immune cells, implying a different...

Want to see the full article?

• Purchase this article for only $3.00