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Cause of Neutropenia Not Predictive of Outcome in HIV+

Published in AIDS Weekly, March 13th, 1995

The cause of neutropenia in HIV seropositive patients is not predictive of outcome of fever and neutropenic episodes, but clinical presentation of patients and concomitant illness is, according to a report from the University of California.

Neutropenia is a common complication of HIV infection and is multifactorial in origin. The most common cause of neutropenia is thought to be ineffective neutrophil production, however, neutrophil antibodies have been implicated in certain circumstances, and drug-induced neutropenia often occurs during administration of zidovudine and medication for the treatment of Pneumocystis carinii pneumonia (PCP), toxoplasmosis, and...

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