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Blood Safety - Indeterminate HIV-1 Follow-Up

"Long-Term Follow-Up of Blood Donors with Indeterminate Human Immunodeficiency Virus Type 1 Results on Western blot."

Published in AIDS Weekly, April 3rd, 1995

According to the authors' abstract of an article published in Transfusion, "Background: At present, tens of thousands of United States blood donors who are at low risk for human immunodeficiency virus type 1 (HIV-1) infection are indefinitely deferred. These persons are repeatedly reactive for HIV-1 antibody in enzyme immunoassay (EIA) and are indeterminate in Western blot. Study Design and Methods: To determine the significance and persistence of anti-HIV-1 reactivity in plasma from volunteer blood donors with HIV-1-indeterminate Western blots, 66 donors were retested for HIV-1 antibody by the same manufacturers' EIA and Western blot 5 to 7 years after the initial...

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