Conference Coverage

Protection Against HIV May Require Mucosal Immunity

Published in AIDS Weekly, April 17th, 1995

Induction of mucosal immunity may be necessary for vaccine prevention of HIV infection, according to researcher Jiri Mestecky of the University of Alabama at Birmingham.

In an invited address to the Second International Conference on Engineered Vaccines for Cancer and AIDS, held March 3-5 in San Francisco, California, Mestecky noted that monkeys that received systemic vaccines against simian immunodeficiency virus (SIV) could resist challenge with injected virus but were not protected when challenged with genital SIV infection.

Most people who acquire HIV infection are exposed via their genital mucosal membranes. And the virus does not have to...

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Source: AIDS Weekly (1995-04-17)

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