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AIDS Weekly

Susan Hasty, Publisher

Table of Contents . . . May 1st, 1995

Non-Subscriber - Summaries Only

Related Areas: Other Issues in AIDS Weekly | Other Publications

Drug Development - New Drug Disrupts "Zipper" Crucial to HIV-1 Infectivity

Pathogenesis - p24 Antibodies Linked to AIDS Nonprogression

Therapy/Retinoic Acid - Ex Vivo CD4+ Cell Death Reduced in AIDS Patients Receiving Retinoic Acid

At-Risk Populations - HIV+ Homeless at Greater Risk for Opportunistic Infections

Diagnosis - Test May Help Predict Speed of AIDS Development

Disease Presentation - Abdominal TB in HIV+ Generally Fatal

Epidemiology - 28 New HIV Cases Reported in Arkansas in Past Month

Epidemiology - High HIV Rates Found in Black Communities near Cities

Evolutionary Biology - Biologist Says Humans Could Have Been Original Host for HIV

Funding - Governor's HIV/AIDS Committee May Continue Without Funds

Funding - Group Announces $150,000 in Grants To Fight AIDS in Maine

Immunology - AIDS-Related Fungal Infections Caused by Cell Defect

Immunology - Cytokine Conference Attracts Hundreds of AIDS Researchers

Industry News/Clinical Study - Human Studies Begin with HIV Vaccine Candidate

Industry News/Clinical Trial - KS Therapy to be Presented to FDA

Industry News/Joint Venture - Option To License Series of Antifungal Compounds Announced

Industry News/Therapy - Promising New Class of Anti-HIV Compounds Presented

International/Greece - Funeral Homes Reportedly Refused To Bury AIDS Patient

Opportunistic Infections - Weak Immune System Foils Prevention of AIDS-Related Disease

Pathogenesis - Novel Risk Markers Predict Progression to AIDS

Pediatrics - Fungemia More Common in HIV+ Children than Documented

Policy - Committee Approves Bill That Could Drop AIDS Teaching in Schools

Prognosis - CD4 Percent Best Indicator of Immune Status in Asplenic HIV-Infected

Testing - State Officials Worry about Home HIV Tests

Therapy - Most Thought To Be TMP-SMZ Intolerant Can Be Desensitized

Transmission - Radiological Procedures Pose Low Risk of HIV Transmission

WHO - Widening Gaps Between Rich and Poor Pose Global Health Threat

Banking - Safety - "HIV Testing in BMT Donors and Recipients."

Cellular Immunity - Vectors - "Defective Retroviruses as Vaccine Vectors."

Drug Development - HIV Vaccines - "Cytotoxic T Lymphocyte and Helper T Cell Responses Following HIV Polynucleotide Vaccination."

Drug Development - HIV Vaccines - "The Immune Response to HIV-1 gp120 Induced by Nucleic Acid Immunization (NAI)."

Immunology - "Context-Dependent Peptide Presentation."

Pathogenesis - "Adoptive Cell-Mediated Immunity to the Purified Protein Derivative (PPD) of a Mycobacterium tuberculosis in Severe Combined Immunodeficient (SCID) Mice."

Pathogenesis - "Loss of CD28 Expression is Associated with Replicative Senescence of T Cells In Vitro and In Vivo."

Adverse Reactions - Scabies Therapy with Lidane - "Neurotoxic Reaction to Lindane in an HIV-Seropositive Patient: An Old Medication's New Problem."

Animal Studies - AZT Metabolism - "Comparative Metabolism of 3'-Azido-3'-Deoxythymidine in Cultured Hepatocytes from Rats, Dogs, Monkeys, and Humans."

Diagnosis - TB of the Foot in HIV Infection - "Tuberculosis of the Foot as the Initial Manifestation of Acquired Immune Deficiency Syndrome: A Report of Two Cases."

Gender Issues - Women and AIDS - "Whose Epidemic Is It? Reviewing the Literature on Women and AIDS."

HIV/Vaccine - European Collaborative Experiment - "Protection of Macaques Against Simian Immunodeficiency Virus Infection with Inactivated Vaccines: Comparison of Adjuvants, Doses and Challenge Viruses."

HIV/Vaccine - Genotypes and Phenotypes - "Neutralizing Antibodies Against Highly Cytopathic Zairian Human Immunodeficiency Type-1 Virus (HIV-1) NDK Are Present in Sera Outside Africa."

Immunology - Chronic Complement Activation - "Decreased Levels of Complement Receptor 1 (CD35) on B Lymphocytes in Persons with HIV Infection."

Immunology - Epidermal Langerhans Cells - "Functional Studies of Epidermal Langerhans Cells and Blood Monocytes in HIV-Infected Persons."

Immunology - Idiopathic CD4+ T-Lymphocytopenia - "Idiopathic CD4+ T-Lymphocytopenia: Analysis of a Patient with Selective IgA Deficiency and No Evidence of HIV Infection."

Immunology - Natural Killer Cells - "Evidence of a Selective Depletion of a CD16+ CD56+ CD8+ Natural Killer Cell Subset During HIV Infection."

Immunology - Pathogenesis of HIV - "Alterations of T-Cell Receptor Variable Region Expression in Human Immunodeficiency Virus Disease."

Kaposi's Sarcoma - Pathogenesis - "Inflammatory Cytokines Induce AIDS Kaposi's Sarcoma-Derived Spindle Cells to Produce and Release Basic Fibroblast Growth Factor and Enhance Kaposi's Sarcoma-Like Lesion Formation in Nude Mice. DOUBLE

Knowledge, Attitudes and Behavior - Adolescents - "AIDS-Risk among Street Children and Youth: Implications for Intervention."

Knowledge, Attitudes and Behavior - Students - "Student Opinion Leaders and HIV/AIDS Knowledge and Risk Behavior."

Neurology - AIDS Dementia Complex Diagnostics - "AIDS Dementia Complex: Evaluation with Proton MR Spectroscopic Imaging."

Neurology - Astrocytes in HIV-1 Encephalitis - "A Regulatory Role for Astrocytes in HIV-1 Encephalitis: An Overexpression of Eicosanoids, Platelet-Activating Factor, and Tumor Necrosis Factor-Alpha by Activated HIV-1DASHSY

Neurology - TNF-Alpha in HIV-1 Encephalopathy - "In Vitro Evidence for a Dual Role of Tumor Necrosis Factor-Alpha in Human Immunodeficiency Virus Type 1 Encephalopathy."

Pneumocystis Carinii - PCR Diagnostics - "The Use of a Nested Polymerase Chain Reaction for Detecting Pneumocystis carinii from Lung and Blood in Rat and Human Infection."

Screening - Saliva-Based Testing - "Use of Saliva as an Alternative to Serum for HIV Screening in Africa."

Therapy - Protease Inhibitor AG1284 - "Formulation Development of An Oral Dosage Form for an HIV Protease Inhibitor, AG1284."

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