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Opportunistic Infections

AIDS Patients with MAC May Be Infected with Different Strains

Published in AIDS Weekly, May 15th, 1995

AIDS patients with polyclonal Mycobacterium avium infection may be infected simultaneously with strains that differ significantly in their antimicrobial susceptibilities.

Organisms of the Mycobacterium avium complex (MAC) are the most common cause of disseminated bacterial infection among patients with AIDS in the United States. Assessment of MAC treatment regimens has been based on both clinical and microbiologic responses, and attempts to correlate pretreatment antimicrobial susceptibility profiles with outcome have been made.

"Most studies have been unable to correlate outcome of MAC treatment with antibiotic susceptibility...

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