Published in AIDS Weekly, May 22nd, 1995
Claudine Boiziau, INSERM, Bordeaux, France, and colleagues said that they synthesized alpha-beta chimeric 17-mer oligodeoxyribonucleotides that contained either 5, 10 or 15 beta nucleotides ("Chimeric Alpha-Beta Oligonucleotides As Antisense Inhibitors of Reverse Transcription," FEBS Letters, March 13, 1995;361(1):41-45).
"The stability of the RNA/chimera hybrids was only slightly affected by the alpha stretch and by the alpha-beta link, as was the affinity of the Moloney murine leukemia virus reverse (MoMLV) transcriptase...
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