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Drug Development

Comtoxins: Theoretical Drugs To Cure AIDS, Cancer, and More

Published in AIDS Weekly, June 19th, 1995

A new, theoretically feasible class of drugs could cure cancer and cell-associated viral or parasitic diseases - including AIDS - and perhaps one day even rejuvenate aging cells.

None of these drugs yet exist but some could be created using currently available biotechnology, according to Alexander Varshavsky of the California Institute of Technology.

Writing in the Proceedings of the National Academy of Sciences ("Codominance and Toxins: A Path to Drugs of Nearly Unlimited Selectivity," PNAS, 1995;92:3663-7), Varshavsky argued that researchers should take advantage of the biological property of codominance to create a new class of drugs called...

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