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Pediatrics - HbOC Vaccination in HIV

"The Immunogenicity of Haemophilus influenzae Type b Conjugate (HbOC) Vaccine in Human Immunodeficiency Virus-Infected and Uninfected Infants."

Published in AIDS Weekly, June 26th, 1995

According to the authors' abstract of an article published in Pediatric Infectious Disease Journal, "Enzyme-linked immunosorbent assay polyribosyl ribitol phosphate (PRP) antibody responses to Haemophilus influenzae type b conjugate vaccine (HbOC) given at 2, 4 and 6 months of age were retrospectively compared in 23 human immunodeficiency virus (HIV) and 24 non-HIV-infected infants. HIV-infected infants were divided into those who were P1 (asymptomatic) or P2 (symptomatic) by 1 year of age. The P2 group was further divided into P2A (mildly symptomatic) and >P2A (rapidly symptomatic) by 1 year of age. The post-third HbOC dose geometric mean antibody titer to PRP was...

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