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Opportunistic Infections

VZV-Associated Encephalitis Reported in AIDS Patient

Published in AIDS Weekly, July 10th, 1995

French researchers report the case of an AIDS patient experiencing brain stem encephalitis due to varicella-zoster virus.

Varicella-zoster virus (VZV) infection is widespread in temperate countries. The course of infection is usually benign in immunocompetent patients, but neurological complications (such as meningoencephalitis, myelitis, and Guillain-Barre syndrome) that are rarely life-threatening develop in 0.1 percent to 0.3 percent of these patients.

In patients who are HIV positive, VZV causes 2 percent of CNS infections and may lead to various neurological syndromes.

"The most characteristic infection is multifocal...

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