Published in AIDS Weekly, July 17th, 1995
Cytopenia is common in HIV, as are neutropenia, lymphopenia, and thrombocytopenia. Dysfunction of the bone marrow stroma has been suggested as a possible mechanism. One of the stroma-derived cytokines, stem cell factor (SCF), has recently been identified as a multipotential growth factor that acts on early hematopoietic progenitor cells of various lineages.
"(SCF) has strong synergistic effects with most of the lineage-restricted cytokines, including...
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