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Combination Therapy

AIDS Drug Combo 'Promising'

Published in AIDS Weekly, August 14th, 1995

The drugs zidovudine (AZT) and 3TC used together appear to be the most effective combination found to combat AIDS, researchers report.

Scientists at the Wellcome Research Laboratories in Kent, United Kingdom (U.K.), said that when AZT is taken with 3TC, the combination overcomes the problem of viral resistance that reduces the effectiveness of either drug taken alone.

In 24-week-long tests on patients infected with AIDS, the combination caused a drop in the amount of viral infection and a rise in the number of lymphocytes, called CD4 cells, that are the target of the virus.

CD4 cells protect the body from infection and it is their...

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