Virology
"Inactivation of Human Immunodeficiency Virus Type 1 by the Amine Oxidase-Peroxidase System."
Published in AIDS Weekly, September 4th, 1995
According to the authors' abstract of an article published in Journal of Clinical Microbiology, "Human immunodeficiency virus type 1 (HIV-1) is rapidly inactivated by exposure to a naturally occurring antimicrobial system consisting of peroxidase, H2 O2 and a halide. Among the potential sources of H2 O2 is the amine oxidase system in which mono-, di-, and polyamines are oxidatively deaminated with the formation of H2 O2 . The polyamine spermine is present at exceptionally high concentrations in semen. We report here that spermine, spermidine, and, to a lesser degree, the synthetic polyamine 15-deoxyspergualin are...
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Source: AIDS Weekly (1995-09-04)
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