Animal Studies (HIV)

Two Poxviruses Offer HIV Protection in Macaques

Published in AIDS Weekly, October 2nd, 1995

Two highly attenuated HIV-2 recombinant poxviruses induced long-lasting protection against HIV in a rhesus macaque study conducted through the U.S. National Institutes of Health's Division of AIDS.

Several HIV vaccine candidates have been found that confer protection against HIV-1, HIV-2 or simian immunodeficiency virus (SIV).

"Protection from HIV-1 infection in chimpanzees has been demonstrated by passive immunization using a monoclonal antibody against the major neutralizing domain (V3) as well as active immunization using the purified envelope glycoprotein gp120, or gp160 together with V3 peptide and Gag antigen or inactivated virus," researcher...

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Source: AIDS Weekly (1995-10-02)

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