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Pathogenesis

Hepatitis C RNA Strongly Increased in HIV Infection

Published in AIDS Weekly, October 23rd, 1995

Hepatitis C virus RNA levels are strongly increased in HIV infection, but there does not appear to be a direct interaction between the two.

The main route of hepatitis C virus (HCV) transmission is parenteral, and most HCV infected patients are either intravenous drug users (IVDU) or recipients of blood products.

"In hemophilic patients, it has been shown that the prevalence of HCV infection in those who received pooled plasma products before HCV screening was close to 100 percent," researcher Bernard Cribier and colleagues wrote ("High Hepatitis C Viremia and Impaired Antibody Response in Patients Co-Infected with HIV," AIDS, October...

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