Therapies (Oral Aphthous Ulcers)

Thalidomide Effective as Treatment for AIDS Related Mouth Ulcers

Published in AIDS Weekly, November 20th, 1995

Thalidomide effectively and safely heals severe mouth ulcers (also called oral aphthous ulcers) in persons with HIV infection, according to an interim analysis of data from a placebo-controlled study supported by the U.S. National Institute of Allergy and Infectious Diseases (NIAID).

The study (ACTG 251), sponsored through NIAID's AIDS Clinical Trials Group, compares the effectiveness and safety of thalidomide with placebo for treating patients with severe oral and esophageal ulcers. In the second or maintenance phase of the study, doctors are evaluating thalidomide's ability to prevent recurrences of ulcers in the mouth or the esophagus.

As a...

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Source: AIDS Weekly (1995-11-20)

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