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AIDS Therapies

FDA Approves 3TC/AZT Combination

Published in AIDS Weekly, December 11th, 1995

The U.S. Food and Drug Administration (FDA) and AIDS advocates will be watching to see whether a newly approved combination of the drugs 3TC and AZT actually prolongs the lives of people with AIDS.

The FDA authorized the use of 3TC in combination with AZT, after only 4-1/2 months of review. The drug's manufacturer must now demonstrate that the therapy produces "clinical benefits," such as a reduction of opportunistic infections, the FDA said.

Glaxo Wellcome Inc., Research Triangle Park, North Carolina, makes both 3TC and AZT. It found that when the two drugs are paired, 3TC appears to boost immune systems and lower the amount of HIV in the blood...

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