Immunization

T-Cell Drop Below 300 Signals Low Response to Vaccines

Published in AIDS Weekly, February 5th, 1996

HIV⁺ adults - particularly travelers - may be at risk of dangerous infections due to impaired antibody responses to booster vaccines.

A Dutch study shows that people with HIV infection may not develop protective antibody responses after vaccination if their CD4⁺ T-cell counts are lower than 300 cells/(mu)L.

Frank P. Kroon of University Hospital, Leiden, Netherlands, and colleagues reported their findings in the journal Clinical Infectious Diseases ("Antibody Response to Diphtheria, Tetanus, and Poliomyelitis Vaccines in Relation to the Number of CD4⁺ T Lymphocytes in Adults Infected with Human Immunodeficiency Virus,"...

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Source: AIDS Weekly (1996-02-05)

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