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Idiopathic CD4+ T-Lymphocytopenia

Condition Reported in HIV Negative Patient

Published in AIDS Weekly, May 13th, 1996

In a letter that appeared in the May 2, 1996, issue of the New England Journal of Medicine (NEJM 1996;334:1202-1203), a Spanish team of physicians described a case of idiopathic CD4+ T-lymphocytopenia in a woman who tested negative for HIV.

"CD4+ T-lymphocytopenia is extremely rare in the absence of ... HIV infection in asymptomatic persons," wrote Dr. Eduardo Fernandez-Cruz of Madrid, Spain. Although the woman had no evidence of HIV infection, she did have a history of unprotected sex with an HIV positive partner who developed AIDS.

Fernandez-Cruz has followed the 30-year-old patient for more than five years, and, despite...

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