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AIDS Therapies (ALX40-4C)

New Treatment Strategy To Block HIV Holds Promise

Published in AIDS Weekly, May 13th, 1996

A laboratory study by researchers at the University of California, Los Angeles (UCLA) AIDS Institute and West Los Angeles Veterans Administration Medical Center (VAMC) has found that a drug can block infection by HIV strains associated with the killing of CD4 cells.

Current therapies for HIV infection, such as zidovudine (AZT), attack the virus after it already has invaded a cell, said study leader William O'Brien, M.D., West Los Angeles VAMC and UCLA associate professor of medicine.

In contrast, O'Brien and his colleagues found that a drug called ALX40-4C appeared to block certain strains of HIV by preventing the virus from entering the cell. "This...

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