Virology (Viral Load)

Treatment May Cause Only Transient Interruption of HIV Infection

Published in AIDS Weekly, August 5th, 1996

A team of German researchers thinks that "complex events occurring in HIV-1 infection ... are only temporarily disturbed by current chemotherapeutic strategies."

Dr. Hans-Jurgen Stellbrink and colleagues from Hamberg "argue for a rapid resumption of virus production and lymphocyte turnover during treatment." Stellbrink's group investigated the short-term kinetics of viral plasma HIV RNA and CD4⁺ T-cell concentrations in ten HIV positive patients (AIDS 1996;10:849-857).

The patients all had different initial CD4⁺ T-cell counts and had been treated with various antiretroviral regimens. The Hamburg team examined the in vivo...

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Source: AIDS Weekly (1996-08-05)

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