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Immunology

"Human Immunodeficiency Virus (HIV) Phenotype and Interleukin-2/Interleukin-10 Ratio Are Associated Markers of Protection and Progression in HIV Infection."

Published in AIDS Weekly, August 19th, 1996

According to the authors' abstract of an article published in Blood, "Human immunodeficiency virus (HIV) isolability, rate of viral replication, HIV phenotype, type 1 and type 2 cytokine production, and CD4 counts were cross-sectionally analyzed in 63 HIV-seropositive (HIV+) individuals to establish possible correlations between virologic and immunologic markers of protection and progression. We observed that these markers are tightly correlated. Thus, lack or low prevalence of HIV isolability and the presence of nonsyncitium inducing strains are associated with the strongest type 1 cytokine production, the weakest type 2 cytokine production, and highest CD4 counts. ...

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