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Gastroenterology

"Uncertain Clinical Significance of Duodenal Mucosal Abnormalities in HIV-Infected Individuals: Results of a Case-Control Study."

Published in AIDS Weekly, September 9th, 1996

According to the authors' abstract of an article published in Journal of Clinical Gastroenterology, "Previous research has described abnormalities of duodenal mucosal morphology in human immunodeficiency virus (HIV)-infected individuals. We wanted to determine the frequency of disturbed villus architecture and investigate its relationship to HIV-related chronic diarrhea. We conducted a case-control study of 120 HIV-infected men, 63 with and 57 without chronic diarrhea. Stools were cultured for bacteria and examined for ova and parasites; esophagogastroduodenoscopy and flexible sigmoidoscopy with mucosal biopsies were performed. Biopsy tissue was examined using light and electron...

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