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Conference Coverage (Vancouver AIDS Conference)

Vaccine Elicits Serum, Mucosal Antibodies Against All HIV Strains

Published in AIDS Weekly, September 16th, 1996

Eight years in the making, a novel HIV immunogen can elicit antibodies that neutralize patient isolates from all over the world.

Depending on how it is formulated and administered, the immunogen can stimulate either serum or mucosal immune responses in animal studies.

"We hope, if all goes well, to do a Phase I clinical trial in HIV seronegatives," said Thomas C. VanCott of the Henry M. Jackson Foundation, Rockville, Maryland.

VanCott described the immunogen, called oligomeric gp160 or ogp160, in a presentation to the XI International Conference on AIDS, held July 7-12, 1996, in Vancouver, British Columbia, Canada.

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